研究方向：蛋白质基生物医用材料

主要研究领域为牦牛功能蛋白的开发与产业化、胶原蛋白材料的设计与功能研究、多肽自组装体系的构建和功效评价、皮肤及骨软骨修复材料。主持国家自然科学基金青年基金项目和甘肃省青年科技基金项目。在Biomacromolecules, International Journal of Biological Macromolecules, Molecular Pharmaceutics, Regenerative Biomaterials, Biomaterials Science等期刊发表SCI论文20余篇。申请发明专利8项。

发表论文

1. Na Li, Zhangwen Liu, Wenhua Li, Linyan Yao*, Jianxi Xiao*. Biocompatible and bioactive yak bone collagen hydrolysates with controllable molecular weight for effective prevention of osteoporosis. Food Bioscience, 2025, 63, 105776. 2) (中科院1区，Top，IF=4.8)
2. Shuangni Shi, Jingting Zhang, Siqi Quan, Yi Yang, Linyan Yao*, Jianxi Xiao*, A highly biocompatible and bioactive transdermal nano collagen for enhanced healing of UV-damaged skin, International Journal of Biological Macromolecules, 272 (2024) 132857. (中科院1区，Top，IF=7.7)
3. Jing Tian, Caihong Fu, Wenhua Li, Na Li, Linyan Yao*, Jianxi Xiao*, Biomimetic tri-layered artificial skin comprising silica gel-collagen membrane-collagen porous scaffold for enhanced full-thickness wound healing, International Journal of Biological Macromolecules, 266 (2024) 131233. (中科院1区，Top，IF=7.7)
4. Linyan Yao, Biyang Ling, Wenjie Huang, Qi Wang, Xiangdong Cai, Jianxi Xiao*, Controllable self-assembly of tyrosine-rich triblock peptides into robust collagen mimetic bioscaffolds for aging skin rejuvenation, Regenerative Biomaterials, 2024, 11, rbae085. (中科院1区，IF=5.6)
5. Linyan Yao, Biyang Ling, Wenjie Huang, Shuangni Shi, Jianxi Xiao*, Versatile triblock peptide self-assembly system to mimic collagen structure and function, Biomacromolecules, 2024, 25, 2520-2530. (中科院2区，Top，IF=5.5)
6. Linyan Yao, Biyang Ling, Sha Zhao, Fansen Yu, Huanxiang Liu, Shenlin Wang, Jianxi Xiao*, Versatile self-assembly of triblock peptides into stable collagen mimetic heterotrimers, International Journal of Molecular Sciences, 2024, 25(12), 6550. (中科院2区，IF=4.9)
7. Linyan Yao, Yue Hu, Zhao Liu, Xiao Ding, Jing Tian, Jianxi Xiao*, Luminescent lanthanide-collagen peptide framework for pH-controlled drug delivery, Molecular Pharmaceutics, 2019, 16, 846-855. (中科院2区，IF=4.5)
8. Shuangni Shi, Jingting Zhang, Yi Yang, Biyang Ling, Linyan Yao*, Jianxi Xiao* Design and evaluation of transdermal nano collagen dressings for enhanced healing of UV-damaged skin. New Journal of Chemistry 12) (中科院3区，IF=2.7)
9. Shuangni Shi, Siqi Quan, Jingting Zhang, Biyang Ling, Linyan Yao*, Jianxi Xiao*, Highly bioactive triple-helical nano collagens for accelerated treatment of photodamaged skin, Biomaterials Science, 2024, 12, 4946-4956. (Cover paper，中科院3区，IF=5.8)
10. Linyan Yao, Manman He, Dongfang Li, Jing Tian, Huanxiang Liu, Jianxi Xiao*, Terminal aspartic acids promote the self-assembly of collagen mimic peptides into nanospheres, RSC Advances, 2018, 8, 2404-2409. (中科院3区，IF=3.9)
11. Linyan Yao, Manman He, Dongfang Li, Huanxiang Liu, Jiang Wu, Jianxi Xiao*, Self-assembling bolaamphiphile-like collagen mimetic peptides, New Journal of Chemistry, 2018, 42, 7439-7444. (中科院3区，IF=2.7)
12. Linyan Yao, Zhao Liu, Jingyuan Yu, Liting Luo, Jie Wang and Jianxi Xiao*, Morphology of osteogenesis imperfecta collagen mimetic peptide assemblies correlate with the identity of glycine-substituting residue, ChemBioChem, 2019, 20, 3013-3019. (Cover paper，中科院4区，IF=2.6)
13. Yi Yang, Bei Tian, Yi Xie, Peng Liu, Linyan Yao* and Jianxi Xiao*, Bioactive triple-helical recombinant collagen gels for improved healing of sunburned skin, Cosmetics, 2024, 11(4), 138. (JCR Q2，IF=3.4)
14. Shuangni Shi, Lili Wang, Linyan Yao*, Jianxi Xiao*, Recent progresses of collagen dressings for chronic skin wound healing, Collagen and Leather, 2023, 5, 31. (Review)
15. Xiaxia Yang, Linyan Yao, Xiuxia Sun, Lili Wang, Jianxi Xiao*, Low-temperature DLP 3D printing of low-concentration collagen methacryloyl for the fabrication of durable and bioactive personalized scaffolds, Chemical Engineering Journal,2024, 497, 155650. (中科院1区，Top，IF=13.3)
16. Xiuxia Sun, Linyan Yao, Caihong Fu, Liting Luo, Jie Wang, Jianxi Xiao*, Detection of target collagen peptides with single amino acid mutation using two fluorescent peptide probes,  Journal of Materials Chemistry B, 2019, 7, 7676-7682. (Cover paper，中科院3区，IF=6.1)
17. Qi Wang, Huiyu Yan, Linyan Yao, Yi Xie, Peng Liu, Jianxi Xiao*, A highly bioactive THPC-crosslinked recombinant collagen hydrogel implant for aging skin rejuvenation, International Journal of Biological Macromolecules, 2024, 266, 131276. (中科院1区，Top，IF=7.7)
18. Xiaoyu Qin, Chen Song, Linyan Yao, Xiangdong Cai, Jianxi Xiao*, A highly specific and versatile biochip for ultra-sensitive quantification of denatured collagen in assessing collagen quality, Analytical Chemistry, 2024, 96, 15640-15647. (中科院1区，Top，IF=6.7)
19. Qi Wang, Huiyu Yan, Linyan Yao, Wenhua Li, Jianxi Xiao*, A highly durable and biocompatible bionic collagen implant with exceptional anti-calcification and collagen regeneration capabilities for improved skin rejuvenation, Materials & Design, 2024, 244, 113177. (中科院2区，IF=7.6)
20. Qi Wang, Huiyu Yan, Linyan Yao, Wenhua Li, Jianxi Xiao*, A highly biocompatible CE-crosslinked collagen implant with exceptional anti-calcification and collagen regeneration capabilities for aging skin rejuvenation, Journal of Materials Chemistry B, 2024, 12, 4467-4477. (中科院3区，IF=6.1)
21. Qi Wang, Huiyu Yan, Linyan Yao, Ying Guo, Jianxi Xiao*, A robust acid-resistant chelating polymer for enhanced stabilization of lead ions in fly ash, BMC Chemistry, 2024, 18, 103. (中科院3区，IF=4.3)
22. Xiuxia Sun, Jun Fan, Caihong Fu, Linyan Yao, Sha Zhao, Jie Wang, Jianxi Xiao*, WS₂ and MoS₂ biosensing platforms using peptides as probe biomolecules, Scientific Reports, 2017, 7, 10290. (中科院3区，IF=3.8)
23. Huixia He, Nannan Wei, Yi Xie, Lili Wang, Linyan Yao, Jianxi Xiao*, Self-assembling triple-helix recombinant collagen hydrogel enriched with tyrosine, ACS Biomaterials Science & Engineering, 2024, 10, 3268-3279. (中科院2区，IF=5.4)
24. Caihong Fu, Shuangni Shi, Jing Tian, Hong Gu, Linyan Yao, Jianxi Xiao*, Non-denatured yak type I collagen accelerates sunburned skin healing by stimulating and replenishing dermal collagen, Biotechnology Reports, 2023, 37, e00778.

授权专利

1. 一种共价光交联多肽、共价光交联多肽自组装形成的胶原蛋白仿生材料，发明人：肖建喜，么林妍，专利号：ZL 202110729121.X
2. 一种三嵌段多肽、三嵌段多肽自组装形成的胶原蛋白仿生材料，发明人：肖建喜，么林妍，专利号：ZL 202110664283.X
3. 一种低内毒素胶原蛋白的制备方法，发明人：肖建喜，么林妍，专利号：ZL 201911091310.8
4. 一种镧系金属介导的胶原多肽及其仿生材料的制备方法，发明人：肖建喜，何曼曼，么林妍，王浪，专利号：ZL 201911091310.8

专著

1. 《胶原蛋白前沿技术与应用》，葡京集团网站出版社，2023-10，编者：肖建喜，么林妍，蔡向东，王莉莉，孙秀霞